
Prodrome stage consisting of malaise, fatigue, etc., Has been describe. Only 1 patient reported pain and burning sensation preceding ecchymosis. Two patients had recurrent symptoms whereas other three were diagnosed during the first episode itself. In other Indian reports, duration ranges from 1 month to 3 years. The duration of complaints range from 1 week to 1 year, with an average of 3. AES in men accounts for 5 % of all cases as reported by Ratnoff et al. However, many cases have been reported in men and children as well. All our cases were of women aged 22-45 years. It is most prevalent among women 19-72 years of age. * Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actionsĪutoerythrocyte sensitization syndrome is a rare clinical syndrome of unknown etiology characterized by recurrent bruising, usually following physical or psychosocial stress. * Please keep in mind that all text is machine-generated, we do not bear any responsibility, and you should always get advice from professionals before taking any actions. While the frequency is highest in women, cases in men and adolescents have also been describe. Numerous somatic complaints may be explored in a diagnostic setting without objective findings and with potential history of multiple surgical procedures. Development generally follows severe stress or emotional trauma or is comorbid with certain Psychiatric psychopathology.

1 Manifestation usually occurs via spontaneous development of painful edematous skin lesions, predominantly in extremities, which may be isolate or multiple, progressing to ecchymosis over the next 24 hours. Psychogenic purpura is regarded primarily as autoimmune vasculopathy with sensitization to phosphatidylserine, component of erythrocyte stroma. Psychogenic purpura, also know as Gardner-Diamond syndrome or autoerythrocyte sensitization syndrome, is an extremely rare condition typically noted in women with Psychiatric comorbidity.
